SNO-y Protein Levels Help Explain Why More Women Develop Alzheimer’s
(Female postmortem brains contain more S-nitrosylated C3 proteins, likely linked to menopause, which instruct immune cells to kill neuronal synapses.)
….. In further in vitro experiments, Lipton and his colleagues found that SNO-C3 activates microglia in the brain and causes them to set their sights on the synapses between neurons, digesting and destroying these connections between brain cells. ….
簡單來說: 女性在得到阿茲海默症的比例比男性多,經過屍檢和體外實驗來看,女性多半產生比較多與阿茲海默症有極高相關性的SNO-C3蛋白質。